Zootherapeutic practices in the Amazon Region: chemical and pharmacological studies of Green-anaconda fat (<em>Eunectes murinus</em>) and alternatives for species conservation

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Authors

  • Camila Ferreira Abrão Universidade Federal do Rio de Janeiro
  • Danilo Ribeiro de Oliveira Universidade Federal do Rio de Janeiro
  • Paulo Passos Universidade Federal do Rio de Janeiro
  • Carla Valéria Rodrigues Pereira Freitas Universidade Estadual de Feira de Santana
  • Amanda Ferreira Santana Universidade Estadual de Feira de Santana
  • Marilene Lopes da Rocha Universidade Estadual de Feira de Santana
  • Antonio Jorge Ribeiro da Silva Universidade Federal do Rio de Janeiro
  • Luzineide Wanderley Tinoco Universidade Federal do Rio de Janeiro https://orcid.org/0000-0002-1299-6242

DOI:

https://doi.org/10.15451/ec2021-02-10.15-1-27

Keywords:

Ethnopharmacology, Chromatography and mass spectrometry analysis, Oleic acid, Linoleic acid, Palmitic acid, Snakes

Abstract

The treatment of diseases with animal resources or their derivatives is a traditional practice worldwide, representing a wide field of research for the elaboration of strategies of management and conservation of the fauna, and contributing to the search for sustainable therapy alternatives. This study presents the therapeutic applications of animal fats to the treatment of several diseases in Pimenteiras do Oeste, state of Rondônia, Brazil. Twelve animals including: mammals, fishes, reptiles and birds are reported as a source of medicinal lard for the treatment of respiratory illnesses (asthma, flu, bronchitis, cough), rheumatism, and earache and as a healing agent (dislocation and wounds). The ethnopharmacological focus of the study was on Green-anaconda fat (Eunectes murinus), which stands out for its frequent local use and the lack of previous chemical studies. The chemical composition of E. murinus fat was analyzed by gas and liquid chromatography, both coupled to mass spectrometry. The main fatty acids identified were oleic, linoleic and palmitic acids, which were also predominant in the composition of the triglycerides. Pharmacological analysis of Green-anaconda fat showed a significant anti-inflammatory effect, which is related to its use by traditional communities. Having confirmed the pharmacological potential of Green-anaconda fat, its fatty acid composition was used as a parameter in the search for vegetable oils from the Amazon Region with a similar composition. This comparative analysis can be of help by proposing therapeutic alternatives for the Amazonian population. The use of plant sources can contribute to the conservation of the aforementioned species.

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Author Biographies

Camila Ferreira Abrão, Universidade Federal do Rio de Janeiro

Instituto de Pesquisas de Produtos Naturais, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373, Bloco H, Rio de Janeiro, RJ, 21941-902, Brazil

Danilo Ribeiro de Oliveira, Universidade Federal do Rio de Janeiro

Faculdade de Farmácia, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373, Bloco A, Rio de Janeiro, RJ, 21941-902, Brazil

Paulo Passos, Universidade Federal do Rio de Janeiro

Departamento de Vertebrados, Museu Nacional, Universidade Federal do Rio de Janeiro, Quinta da Boa Vista, São Cristóvão, Rio de Janeiro, RJ, 20940-040, Brazil

Carla Valéria Rodrigues Pereira Freitas, Universidade Estadual de Feira de Santana

Universidade Estadual de Feira de Santana, Avenida Transnordestina, s/n - Novo Horizonte, Caixa Postal 252 e 294, Módulo I - MA 14, Feira de Santana, Bahia, 44.036-900, Brazil

Amanda Ferreira Santana, Universidade Estadual de Feira de Santana

Universidade Estadual de Feira de Santana, Avenida Transnordestina, s/n - Novo Horizonte, Caixa Postal 252 e 294, Módulo I - MA 14, Feira de Santana, Bahia, 44.036-900, Brazil

 

Marilene Lopes da Rocha, Universidade Estadual de Feira de Santana

Universidade Estadual de Feira de Santana, Avenida Transnordestina, s/n - Novo Horizonte, Caixa Postal 252 e 294, Módulo I - MA 14, Feira de Santana, Bahia, 44.036-900, Brazil

Antonio Jorge Ribeiro da Silva, Universidade Federal do Rio de Janeiro

Instituto de Pesquisas de Produtos Naturais, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373, Bloco H, Rio de Janeiro, RJ, 21941-902, Brazil

Luzineide Wanderley Tinoco, Universidade Federal do Rio de Janeiro

Instituto de Pesquisas de Produtos Naturais, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373, Bloco H, Rio de Janeiro, RJ, 21941-902, Brazil

References

Ahmad TB, Rudd D, Kotiw M, Liu L, Benkendorff K (2019) Correlation between fatty acid profile and anti-inflammatory activity in common Australian seafood by-products. Marine Drugs 17:1–20 DOI: https://doi.org/10.3390/md17030155

Al-Snafi AE (2018) The Pharmacological Effects of Helianthus Annuus- a Review. Indo American Journal of Pharmaceutical Sciences 5:1745–1756

Albuquerque FEA, Minervino AHH, Miranda M, Herrero-Latorre C, Barrêto Júnior RA, Oliveira FLC, Sucupira MCA, Ortolani EL, López-Alonso M (2020) Toxic and essential trace element concentrations in fish species in the Lower Amazon, Brazil. Science of the Total Environment 732:138983 DOI: https://doi.org/10.1016/j.scitotenv.2020.138983

Alkhalaf MI, Alansari WS, Ibrahim EA, ELhalwagy MEA (2019) Anti-oxidant, anti-inflammatory and anti-cancer activities of avocado (Persea americana) fruit and seed extract. Journal of King Saud University - Science 31:1358–1362 DOI: https://doi.org/10.1016/j.jksus.2018.10.010

Almeida, R.N.; Oliveira TML (2006) Triagem Farmacológica Comportamental. In: Almeida RN (ed) Psicofarmacologia: fundamentos práticos. Guanabara Koogan, Rio de Janeiro, pp. 131–137

Alves RR da N, Vieira WL da S, Santana GG (2008a) Reptiles used in traditional folk medicine: Conservation implications. Biodiversity and Conservation 17:2037–2049 DOI: https://doi.org/10.1007/s10531-007-9305-0

Alves RRN, Albuquerque UP (2013) Animals as a source of drugs: Bioprospecting and biodiversity conservation. Animals in Traditional Folk Medicine: Implications for Conservation. Springer-Verlag Berlin Heidelberg, pp. 67–89 DOI: https://doi.org/10.1007/978-3-642-29026-8_5

Alves RRN, Alves HN (2011) The faunal drugstore: Animal-based remedies used in traditional medicines in Latin America. Journal of Ethnobiology and Ethnomedicine 7:9 DOI: https://doi.org/10.1186/1746-4269-7-9

Alves RRN, Borges AKM, Barboza RRD, Souto WMS, Gonçalves‐Souza T, Provete DB, Albuquerque UP (2020) A global analysis of ecological and evolutionary drivers of the use of wild mammals in traditional medicine. Mammal Review mam.12233 DOI: https://doi.org/10.1111/mam.12233

Alves RRN, Lima HN, Tavares MC, Souto WMS, Barboza RRD, Vasconcellos A (2008) Animal-based remedies as complementary medicines in Santa Cruz do Capibaribe, Brazil. BMC Complementary and Alternative Medicine 8:44 DOI: https://doi.org/10.1186/1472-6882-8-44

Alves RRN, Medeiros MFT, Albuquerque UP, Rosa IL (2013a) From past to present: Medicinal animals in a historical perspective. Animals in Traditional Folk Medicine: Implications for Conservation. Springer-Verlag Berlin Heidelberg, pp. 11–23 DOI: https://doi.org/10.1007/978-3-642-29026-8_2

Alves RRN, Neta RO de S, Trovão DM de BM, Barbosa JE de L, Barros AT, Dias TLP (2012) Traditional uses of medicinal animals in the semi-arid region of northeastern Brazil. Journal of Ethnobiology and Ethnomedicine 8:41 DOI: https://doi.org/10.1186/1746-4269-8-41

Alves RRN, Pinto LCL, Barboza RD, Raynner, Souto WMS, Enderson R, Oliveira MCC, Vieira WLS (2013b) A Global Overview of Carnivores Used in Traditional Medicine. In: Alves RR da N, Rosa IL (eds) Animals in Traditional Folk Medicine: Implications for conservation. Springer-Verlag, Berlin Heidelberg, pp. 171–206 DOI: https://doi.org/10.1007/978-3-642-29026-8_9

Alves RRN, Rosa IL (2006) From cnidarians to mammals: The use of animals as remedies in fishing communities in NE Brazil. Journal of Ethnopharmacology 107:259–276 DOI: https://doi.org/10.1016/j.jep.2006.03.007

Alves RRN, Rosa IL (2007a) Zootherapeutic practices among fishing communities in North and Northeast Brazil: A comparison. Journal of Ethnopharmacology 111:82–103 DOI: https://doi.org/10.1016/j.jep.2006.10.033

Alves RRN, Rosa IL (2010) Trade of Animals Used in Brazilian Traditional Medicine: Trends and Implications for Conservation. Human Ecology 38:691–704 DOI: https://doi.org/10.1007/s10745-010-9352-0

Alves RRN, Rosa IL, Albuquerque UP, Cunningham AB (2013c) Medicine from the Wild: An Overview of the Use and Trade of Animal Products in Traditional Medicines. In: Alves RRN, Rosa I. (eds) Animals in Traditional Folk Medicine: Implications for Conservation. Springer Heidelberg, pp. 67–89 DOI: https://doi.org/10.1007/978-3-642-29026-8_3

Alves RRN, Rosa IML (2007b) Biodiversity, traditional medicine and public health: Where do they meet? Journal of Ethnobiology and Ethnomedicine 3:1–9 DOI: https://doi.org/10.1186/1746-4269-3-14

Alves RRN, Santana GG, I.L. R (2013d) The Role of Animal-Derived Remedies as Complementary Medicine in Brazil. In: Alves RRN, Rosa IL (eds) Animals in Traditional Folk Medicine: Implications for Conservation. Springer-Verlag, Berlin Heidelberg, pp. 289–301

Alves RRN, Santana GG, Rosa IL (2013e) The role of animal-derived remedies as complementary medicine in Brazil. Animals in Traditional Folk Medicine: Implications for Conservation. Springer-Verlag Berlin Heidelberg, pp. 289–301 DOI: https://doi.org/10.1007/978-3-642-29026-8_13

Alves RRN, Vieira WLS, Santana GG, Vieira KS, Montenegro PFGP (2013f) Herpetofauna used in traditional folk medicine: Conservation implications. Animals in Traditional Folk Medicine: Implications for Conservation. Springer-Verlag Berlin Heidelberg, pp. 109–133 DOI: https://doi.org/10.1007/978-3-642-29026-8_7

Aparna V, Dileep K V., Mandal PK, Karthe P, Sadasivan C, Haridas M (2012) Anti-Inflammatory Property of n-Hexadecanoic Acid: Structural Evidence and Kinetic Assessment. Chemical Biology and Drug Design 80:434–439 DOI: https://doi.org/10.1111/j.1747-0285.2012.01418.x

de Araújo VF, Petry AC, Echeverria RM, Fernandes EC, Pastore Jr F (2007) Plantas da Amazônia para Produção Cosmética -Uma Abordagem Química. Universidade de Brasília, Brasília, p. 214

Baldin N, Munhoz EMB (2012) Educação ambiental comunitária: uma experiência com a técnica de pesquisa snowball (bola de neve). REMEA - Revista Eletrônica do Mestrado em Educação Ambiental 27:46–60

Barkoot M, Albejawi A, Alhadri A, Albalawi S, Al Awwas M, Alameer M, Alshlaqi B, Alshammary A, Alameer D, Alhawiti M (2018) The impact of fish oil supplementation in patients with rheumatoid arthritis. International Journal Of Community Medicine And Public Health 5:2637 DOI: https://doi.org/10.18203/2394-6040.ijcmph20182493

Le Bars D, Gozariu M, Cadden SW (2001) Animal Models of Nociception. Pharmacological Reviews 53:597–652

Begossi A (1992) Food Taboos at Buzios Island (Brazil): Their Significance and Relation to Folk Medicine. Journal of Ethnobiology 12:117–139

Begossi A, Braga FM de S (1992) Food taboos and folk medicine among fishermen from the Tocantins River (Brazil). Amazoniana 12:341–352

Begossi A, Ramires M (2013) Fish Folk Medicine of Caiçara (Atlantic Coastal Forest) and Caboclo (Amazon Forest) Communities. In: Alves RRN, Rosa IL (eds) Animals in Traditional Folk Medicine. Springer Heidelberg New York Dordrecht London, New York, p. 492 DOI: https://doi.org/10.1007/978-3-642-29026-8_6

Benítez G (2011) Animals used for medicinal and magico-religious purposes in western Granada Province, Andalusia (Spain). Journal of Ethnopharmacology 137:1113–1123 DOI: https://doi.org/10.1016/j.jep.2011.07.036

Bezerra NKMS, Barros TL, Coelho NPMF (2015) A ação do óleo de pequi (Caryocar brasiliense) no processo cicatricial de lesões cutâneas em ratos. Revista Brasileira de Plantas Medicinais 17:875–880 DOI: https://doi.org/10.1590/1983-084X/14_061

Bisol CA (2012) Estratégias de pesquisa em contextos de diversidade cultural: entrevistas de listagem livre, entrevistas com informantes-chave e grupos focais. Estudos de Psicologia (Campinas) 29:719–726 DOI: https://doi.org/10.1590/S0103-166X2012000500008

Bitencourt BLG, Lima PGC, Barros FB (2014) Comércio e uso de plantas e animais de importância mágico-religiosa e medicinal no mercado público do Guamá, Belém do Pará. Revista FSA 11:96–158 DOI: https://doi.org/10.12819/2014.11.3.5

Bony E, Boudard F, Brat P, Dussossoy E, Portet K, Poucheret P, Giaimis J, Michel A (2012) Awara (Astrocaryum vulgare M.) pulp oil: Chemical characterization, and anti-inflammatory properties in a mice model of endotoxic shock and a rat model of pulmonary inflammation. Fitoterapia 83:33–43 DOI: https://doi.org/10.1016/j.fitote.2011.09.007

Bora PS, Narain N, Rocha RVM, De AC, Monteiro O, De R, Moreira A (2009) Characterization of the oil and protein fractions of tucuma (Astrocaryum Vulgare Mart.) Fruit pulp and seed kernel caracterización de las fracciones protéicas y lipídicas de pulpa y semillas de tucuma (Astrocaryum Vulgare Mart.) Caracterización das fracci. CYTA - Journal of Food 3:111–116 DOI: https://doi.org/10.1080/11358120109487654

Borah MP, Prasad SB (2017) Ethnozoological study of animals based medicine used by traditional healers and indigenous inhabitants in the adjoining areas of Gibbon Wildlife Sanctuary, Assam, India. Journal of Ethnobiology and Ethnomedicine 13:1–13 DOI: https://doi.org/10.1186/s13002-017-0167-6

Castillo L, Ladio and A (2019) Zootherapy and rural livestock farmers in semiarid Patagonia: the transfer of animal aptitudes for health. Ethnobiology and Conservation 8:1–24 DOI: https://doi.org/10.15451/ec2019-01-8.02-1-23

Cimen FK, Kockara N, Turkoglu M, Dundar C, Cetin N, Suleyman B, Coban A, Yarali O, Malkoc I, Suleyman H (2017) Effect of sheep tail fat on the knee joint cartilage injury induced in rats with formalin. International Journal of Clinical and Experimental Medicine 10:7573–7581

Cleland LG, James MJ, Proudman SM (2003) The role of fish oils in the treatment of rheumatoid arthritis. Drugs 63:845–853 DOI: https://doi.org/10.2165/00003495-200363090-00001

Costa-Neto EM (2005) Animal-based medicines: biological prospection and the sustainable use of zootherapeutic resources. Anais da Academia Brasileira de Ciências 77:33–43 DOI: https://doi.org/10.1590/S0001-37652005000100004

Coutinho HD. (2010) Validação de atividades biológicas e isolamento de produtos naturais de origem animal. In: Costa-Neto, E.M.; Alves RRN (ed) Zooterapia: os animais na medicina popular brasileira. NUPEEA, Recife, pp. 189–197

Cragg GM, Newman DJ (2013) Natural products: A continuing source of novel drug leads. Biochimica et Biophysica Acta - General Subjects 1830:3670–3695 DOI: https://doi.org/10.1016/j.bbagen.2013.02.008

Da Cruz Rodrigues AM, Darnet S, Da Silva LHM (2010) Fatty acid profiles and tocopherol contents of buriti (mauritia flexuosa), patawa (oenocarpus bataua), tucuma (astrocaryum vulgare), mari (poraqueiba paraensis) and Inaja (Maximiliana Maripa) fruits. Journal of the Brazilian Chemical Society 21:2000–2004 DOI: https://doi.org/10.1590/S0103-50532010001000028

Cunha VMB, Silva MP da, Sousa SHB de, Bezerra P do N, Menezes EGO, Silva NJN da, Banna DAD da S, Araújo ME, Carvalho Junior RN de (2019) Bacaba-de-leque (Oenocarpus distichus Mart.) oil extraction using supercritical CO2 and bioactive compounds determination in the residual pulp. Journal of Supercritical Fluids 144:81–90 DOI: https://doi.org/10.1016/j.supflu.2018.10.010

Dubuisson D, Dennis SG (1977) The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain 4:161–174 DOI: https://doi.org/10.1016/0304-3959(77)90130-0

Dunham NW, Miya TS (1957) A Note on a Simple Apparatus for Detecting Neurological Deficit in Rats and Mice**College of Pharmacy, University of Nebraska, Lincoln 8. Journal of the American Pharmaceutical Association (Scientific ed.) 46:208–209 DOI: https://doi.org/10.1002/jps.3030460322

Falodun A, Owolabi OJ, Osahon O (2008) Physicochemical, antimicrobial and anti-inflammatory evaluation of fixed oil from Boa constrictor. Acta Poloniae Pharmaceutica - Drug Research 65:477–480

Favacho HAS, Oliveira BR, Santos KC, Medeiros BJL, Sousa PJC, Perazzo FF, Carvalho JCT (2011) Anti-inflammatory and antinociceptive activities of Euterpe oleracea oil. Brazilian Journal of Pharmacognosy 21:105–114 DOI: https://doi.org/10.1590/S0102-695X2011005000007

Fernandes LC, Silva RB da, Guimarães SCP (Coord. ). (2010) Zoneamento socioeconômico e ecológico do estado de Rondônia: vinte e um anos de zoneamento socioeconômico e ecológico do estado de Rondônia. Planejamento para o desenvolvimento sustentável e proteção ambiental. SEDAM, Porto Velho

Ferreira AM, De Souza BMV, Rigotti MA, Loureiro MRD (2012) The use of fatty acids in wound care: An integrative review of the Brazilian literature. Revista da Escola de Enfermagem 46:752–760 DOI: https://doi.org/10.1590/S0080-62342012000300030

Ferreira FS, Brito A V., Ribeiro SC, Saraiva AAF, Almeida WO, Alves RRN (2009a) Animal-based folk remedies sold in public markets in Crato and Juazeiro do Norte, Ceará, Brazil. BMC Complementary and Alternative Medicine 9:1–8 DOI: https://doi.org/10.1186/1472-6882-9-17

Ferreira FS, Brito S V., Costa JGM, Alves RRN, Coutinho HDM, Almeida W de O (2009b) Is the body fat of the lizard Tupinambis merianae effective against bacterial infections? Journal of Ethnopharmacology 126:233–237 DOI: https://doi.org/10.1016/j.jep.2009.08.038

Ferreira FS, Brito S V., Sales DL, Menezes IRA, Coutinho HDM, Souza EP, Almeida WO, Alves RRN (2014) Anti-inflammatory potential of zootherapeutics derived from animals used in Brazilian traditional medicine. Pharmaceutical Biology 52:1403–1410 DOI: https://doi.org/10.3109/13880209.2014.894091

Ferreira FS, Brito SV, de Oliveira Almeida W, Alves RRN (2016) Conservation of animals traded for medicinal purposes in Brazil: Can products derived from plants or domestic animals replace products of wild animals? Regional Environmental Change 16:543–551 DOI: https://doi.org/10.1007/s10113-015-0767-4

Ferreira FS, Fernandes-Ferreira H, Léo Neto NA, Brito S V., Alves RRN (2013) The trade of medicinal animals in Brazil: Current status and perspectives. Biodiversity and Conservation 22:839–870 DOI: https://doi.org/10.1007/s10531-013-0475-7

Fischer ML, Palodeto MFT, dos Santos EC (2018) Uso de animais como zooterápicos: Uma questão bioética. Historia, Ciencias, Saude - Manguinhos 25:217–243 DOI: https://doi.org/10.1590/s0104-59702018000100013

Hadley NF, Christie WW (1974) The lipid composition and triglyceride structure of eggs and fat bodies of the lizard Sceloporus jarrovi. Comparative Biochemistry and Physiology -- Part B: Biochemistry and 48:275–284 DOI: https://doi.org/10.1016/0305-0491(74)90204-1

Hunskaar S, Fasmer OB, Hole K (1985) Formalin test in mice, a useful technique for evaluating mild analgesics. Journal of Neuroscience Methods 14:69–76 DOI: https://doi.org/10.1016/0165-0270(85)90116-5

IBGE (2019) Busca | IBGE. [https://www.ibge.gov.br/busca.html?searchword=pimenteiras+do+oeste] Accessed May 14, 2020

ICMBIO M (2018) Livro Vermelho da Fauna Brasileira Ameaçada de Extinção. 1a. Vol.1 ed. ICMBio/MMA, Brasília

Jesus M. (2014) Histórico. [http://www.pimenteirasdooeste.ro.gov.br./index.php/o-municipio/historico] Accessed May 14, 2020

Leocádia GI (2018) A luta pelo direito de re"existir" | | Livro-reportagem em revista. [https://livro-reportagem.com.br/a-luta-pelo-direito-de-reexistir/] Accessed May 14, 2020

Lev E (2003) Traditional healing with animals (zootherapy): Medieval to present-day Levantine practice. Journal of Ethnopharmacology 85:107–118 DOI: https://doi.org/10.1016/S0378-8741(02)00377-X

De Lima A, Silva AMDO, Trindade RA, Torres RP, Mancini-Filho J (2007) Composição química e compostos bioativos presentes na polpa e na amêndoa do pequi (Caryocar brasiliense, Camb.). Revista Brasileira de Fruticultura 29:695–698 DOI: https://doi.org/10.1590/S0100-29452007000300052

Lima PGC, Coelho-Ferreira M, Oliveira R (2011) Plantas medicinais em feiras e mercados públicos do distrito florestal sustentável da BR-163, estado do Pará, Brasil. Acta Botanica Brasilica 25:422–434 DOI: https://doi.org/10.1590/S0102-33062011000200018

Lopes RM, Da Silva JP, Vieira RF, Da Silva DB, Gomes I da S, Agostini-Costa T da S (2012) Composição de Ácidos Graxos em Polpa de Frutas Nativas do Cerrado. Revista Brasileira de Fruticultura 34:635–640 DOI: https://doi.org/10.1590/S0100-29452012000200041

Maciel MAM, Pinto AC, Veiga VF, Grynberg NF, Echevarria A (2002) Plantas medicinais: A necessidade de estudos multidisciplinares. Quimica Nova 25:429–438 DOI: https://doi.org/10.1590/S0100-40422002000300016

Mambrim MCT, Barrera-Arellano D (1997) Caracterización de aceites de frutos de palmeras de la región amazónica del Brasil. Grasas y Aceites 48:154–158 DOI: https://doi.org/10.3989/gya.1997.v48.i3.783

MAPA (2018) Legislação: Instrução Normativa MAPA 81, de 19/12/2018 | Defesa Agropecuária do Estado de São Paulo. [https://www.defesa.agricultura.sp.gov.br/legislacoes/instrucao-normativa-mapa-81-de-19-12-2018,1239.html] Accessed May 20, 2020

Marques JGW (1995) Pescando pescadores : etnoecologia abrangente no baixo Sao Francisco alagoano. São Paulo

Martins M, Maia Filho ALM, Costa CLS, Coelho NPMF, Costa MS, Carvalho RA (2011) Ação anti-infl amatória da fração lipídica do Ovis aries associado ao ultrassom terapêutico em modelo experimental de tendinite em ratos (Rattus norvegicus). Revista Brasileira de Fisioterapia 15:297–302 DOI: https://doi.org/10.1590/S1413-35552011000400007

Martius KFP von (1939) Natureza, doenças, medicina e remédios dos índios brasileiros. Brasiliana V. 154. Ed. Nacional, São Paulo, p. 286

Marx F, Andrade EHA, Maia JG (1997) Chemical composition of the fruit pulp of Caryocar villosum. European Food Research and Technology 204:442–444 DOI: https://doi.org/10.1007/s002170050110

Marx F, Andrade EHA, Maia JG (1998) Chemical composition of the fruit of Solanum sessiliflorum. European Food Research and Technology 206:364–366 DOI: https://doi.org/10.1007/s002170050274

Matos FJ de A (2007) Plantas medicinais: guia de seleção e emprego de plantas usadas em fitoterapia no Nordeste do Brasil. Universidade Federal do Ceará, UFC, Fortaleza

Mattei, R., Franca CIF (2006) Testes gerais para confirmar a ação central. In: ALMEIDA RN (ed) Psicofarmacologia: fundamentos práticos. Guanabara Koogan, Rio de Janeiro, pp. 138–142

McCue MD (2008) Fatty acid analyses may provide insight into the progression of starvation among squamate reptiles. Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology 151:239–246 DOI: https://doi.org/10.1016/j.cbpa.2008.06.034

MEB (1993) Popular medicine recipes. MEB - Movimento de Educação de Base. 26

Miranda E (2016) O quê as sucuris matam e porque pessoas matam sucuris - ((o))eco. [https://www.oeco.org.br/colunas/colunistas-convidados/o-que-as-sucuris-matam-e-porque-pessoas-matam-sucuris/] Accessed February 1, 2021

Mishra B, Akhila M, Thomas A, Benny B, Assainar H (2020) Formulated Therapeutic Products of Animal Fats and Oils: Future Prospects of Zootherapy. International Journal of Pharmaceutical Investigation 10:112–116 DOI: https://doi.org/10.5530/ijpi.2020.2.20

Montes L V, Broseghini LP, Andreatta FS, Silva AG (2009) Evidências para o uso da óleo-resina de copaíba na cicatrização de ferida – uma revisão sistemática. Natureza online 7:61–67

Morais SM de, Nascimento JET do, Silva AA de S, Junior JERH, Pinheiro DCSN, Oliveira RV de (2017) Fatty Acid Profile and Anti-Inflammatory Activity of Fixed Plant Oils. Acta Scientiae Veterinariae 45:8 DOI: https://doi.org/10.22456/1679-9216.79403

Nagy K, Tiuca I-D (2017) Importance of Fatty Acids in Physiopathology of Human Body. Fatty Acids. InTech, p. 22 DOI: https://doi.org/10.5772/67407

de Oliveira DR, Costa ALMA, Leitão GG, Castro NG, dos Santos JP, Leitão SG (2011) Estudo etnofarmacognóstico da saracuramirá (Ampelozizyphus amazonicus Ducke), uma planta medicinal usada por comunidades quilombolas do Município de Oriximiná-PA, Brasil. Acta Amazonica 41:383–392 DOI: https://doi.org/10.1590/S0044-59672011000300008

Oliveira ES, Torres DF, Brooks SE, Alves RRN (2010) The medicinal animal markets in the metropolitan region of Natal City, northeastern Brazil. Journal of Ethnopharmacology 130:54–60 DOI: https://doi.org/10.1016/j.jep.2010.04.010

Oliveira FDS, De Sousa DP, De Almeida RN (2008) Antinociceptive effect of hydroxydihydrocarvone. Biological and Pharmaceutical Bulletin 31:588–591 DOI: https://doi.org/10.1248/bpb.31.588

Di Pasquale MG (2009) The essentials of essential fatty acids. Journal of Dietary Supplements 6:143–161 DOI: https://doi.org/10.1080/19390210902861841

Penrod J, Preston DB, Starks MT, Cain RE (2003) A Discussion of Chain Referral As a Method of Sampling Hard-to-Reach Populations. Journal of Transcultural Nursing 14:100–107 DOI: https://doi.org/10.1177/1043659602250614

Pereira LM, Hatanaka E, Martins EF, Oliveira F, Liberti EA, Farsky SH, Curi R, Pithon-Curi TC (2008) Effect of oleic and linoleic acids on the inflammatory phase of wound healing in rats. Cell Biochemistry and Function 26:197–204 DOI: https://doi.org/10.1002/cbf.1432

Pérez-Vich B, Velasco L, Fernández-Martínez JM (1998) Determination of seed oil content and fatty acid composition in sunflower through the analysis of intact seeds, husked seeds, meal and oil by near-infrared reflectance spectroscopy. Journal of the American Oil Chemists’ Society 75:547–555 DOI: https://doi.org/10.1007/s11746-998-0064-1

Pinheiro ZC da S, Sahr CLL (2016) Imaginário e espacialidade vivida em narrativas quilombolas, Pimenteiras do Oeste– Rondônia, Brasil. 160–176 DOI: https://doi.org/10.5216/ag.v10i1.35129

da Ponte FAF, Rodrigues JS, Malveira JQ, Filho JASR, Albuquerque MCG (2017) Avaliação físico-química dos óleos de babaçu (Orbignya speciosa) e coco (Cocos nucifera) com elevado índice de acidez e dos ácidos graxos (C6 a C16). Scientia Plena 13:1–8 DOI: https://doi.org/10.14808/sci.plena.2017.085301

Quinlan M (2005) Considerations for Collecting Freelists in the Field: Examples from Ethobotany. Field Methods 17:219–234 DOI: https://doi.org/10.1177/1525822X05277460

Rahman MT, Sobur MA, Islam MS, Ievy S, Hossain MJ, Zowalaty MEE, Rahman AMMT, Ashour HM (2020) Zoonotic diseases: Etiology, impact, and control. Microorganisms 8:1–34 DOI: https://doi.org/10.3390/microorganisms8091405

Rogez H, Buxant R, Mignolet E, Souza JNS, Silva EM, Larondelle Y (2004) Chemical composition of the pulp of three typical Amazonian fruits: Araça-boi (Eugenia stipitata), bacuri (Platonia insignis) and cupuaçu (Theobroma grandiflorum). European Food Research and Technology 218:380–384 DOI: https://doi.org/10.1007/s00217-003-0853-6

Santos CAB, Lima JRB (2009) Estudo Etnozoológico: o comercio de produtos de origem animal utilizados como produtos farmacológicos nas cidades de Paulo Afonso-BA e Delmiro Gouveia-AL. Revista Ouricuri 1:115–128

Schmeda-Hirschmann G, Delporte C, Valenzuela-Barra G, Silva X, Vargas-Arana G, Lima B, Feresin GE (2014) Anti-inflammatory activity of animal oils from the Peruvian Amazon. Journal of Ethnopharmacology 156:9–15 DOI: https://doi.org/10.1016/j.jep.2014.08.010

Serra JL, Rodrigues AM da C, de Freitas RA, Meirelles AJ de A, Darnet SH, Silva LHM da (2019) Alternative sources of oils and fats from Amazonian plants: Fatty acids, methyl tocols, total carotenoids and chemical composition. Food Research International 116:12–19 DOI: https://doi.org/10.1016/j.foodres.2018.12.028

Silva AL da (2008) Animais medicinais: conhecimento e uso entre as populações ribeirinhas do rio Negro, Amazonas, Brasil. Boletim do Museu Paraense Emílio Goeldi. Ciências Humanas 3:343–357 DOI: https://doi.org/10.1590/S1981-81222008000300005

Silva LR (2018) Propriedades físico-químicas e perfil dos ácidos graxos do óleo da andiroba. Nativa 6:147 DOI: https://doi.org/10.31413/nativa.v6i2.4729

Silva NLG et al. (2010) Zooterápicos utilizados em comunidades rurais do município de Sumé, semiárido da Paraíba, Nordeste do Brasil. In: COSTA NETO, E.M.C.; ALVES RRN (ed) Zooterapia: os animais na medicina popular brasileira. NUPEEA, pp. 243–267

SisGen (2017) SisGen. [https://www.mma.gov.br/patrimonio-genetico/conselho-de-gestao-do-patrimonio-genetico/sis-gen] Accessed May 24, 2020

Souto WMS, Barboza RRD, Fernandes-Ferreira H, Júnior AJCM, Monteiro JM, Abi-chacra É de A, Alves RRN (2018) Zootherapeutic uses of wildmeat and associated products in the semiarid region of Brazil: General aspects and challenges for conservation. Journal of Ethnobiology and Ethnomedicine 14:60 DOI: https://doi.org/10.1186/s13002-018-0259-y

Souto WMS et al (2011) Breve revisão sobre fauna medicinal no Brasil. 11:201–210 DOI: https://doi.org/10.13102/scb71

Souza E, Werneck FP, Matos LB, Fraga R De (2017) Zootherapy in the Amazon: green anaconda (Eunectes murinus) fat as a natural medicine to treat wounds. 47:341–348 DOI: https://doi.org/10.1590/1809-4392201702202

Tougan UP, Youssao IA, Yayi EL, Kpodekon MT, Heuskin S, Beckers Y, Mensah GA, Koutinhouin BG, Lognay G, Thewis A (2018) Fatty Acids Composition of Meat of Five Native Chicken (Gallus gallus ) Ecotypes of Benin Reared under Organic or Conventional system.

Ugwudike PO, OkakaA N, Ezeonu FE, Neboh EE (2013) Python fat: effect on collagen levels of human keloid tissue. International Journal of Biological & Medical Research 4:3219–3221

Venancio MMH, Mazzafera, Paulo Carvalho, Cássia Limonta Silveira, Lisandra Herica Azevedo Filho JA, Bazzo, Bárbara Regina Colombo CA (2016) Teor de óleo e perfil de ácidos graxos durante o desenvolvimento de frutos de macaúba.

Vinuto J (2014) A amostragem em bola de neve na pesquisa qualitativa: um debate em aberto. Temáticas 22:203–220 DOI: https://doi.org/10.20396/tematicas.v22i44.10977

Weitz D, Weintraub H, Fisher E, Schwartzbard AZ (2010) Fish oil for the treatment of cardiovascular disease. Cardiology in Review 18:258–263 DOI: https://doi.org/10.1097/CRD.0b013e3181ea0de0

Whiting MJ, Williams VL, Hibbitts TJ (2011) Animals traded for traditional medicine at the Faraday market in South Africa: species diversity and conservation implications. Journal of Zoology 284:84–96 DOI: https://doi.org/10.1111/j.1469-7998.2010.00784.x

Whiting MJ, Williams VL, Hibbitts TJ (2013) Animals traded for traditional medicine at the faraday market in South Africa: Species diversity and conservation implications. Animals in Traditional Folk Medicine: Implications for Conservation. Springer-Verlag Berlin Heidelberg, pp. 421–473 DOI: https://doi.org/10.1007/978-3-642-29026-8_19

Yoganathan S, Nicolosi R, Wilson T, Handelman G, Scollin P, Tao R, Binford P, Orthoefer F (2003) Antagonism of croton oil inflammation by topical emu oil in CD-1 mice. Lipids 38:603–607 DOI: https://doi.org/10.1007/s11745-003-1104-y

Zanoschi C, Ciobanu C, Verbuţă A, Frîncu D (1991) The efficiency of some natural drugs in the treatment of burns. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 95:63–5

Zhao G, Etherton TD, Martin KR, Vanden Heuvel JP, Gillies PJ, West SG, Kris-Etherton PM (2005) Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cells. Biochemical and Biophysical Research Communications 336:909–917 DOI: https://doi.org/10.1016/j.bbrc.2005.08.204

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02/19/2021 — Updated on 02/19/2021

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Ferreira Abrão, C. ., Ribeiro de Oliveira, D. ., Passos, P. ., Rodrigues Pereira Freitas, C. V. ., Ferreira Santana, A. ., Lopes da Rocha, M. ., Ribeiro da Silva, A. J. ., & Tinoco, L. W. (2021). Zootherapeutic practices in the Amazon Region: chemical and pharmacological studies of Green-anaconda fat (<em>Eunectes murinus</em>) and alternatives for species conservation. Ethnobiology and Conservation, 10. https://doi.org/10.15451/ec2021-02-10.15-1-27

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